Nanotechnology could potentially radically change the global politcs and international relations.

Any country with a "nano" assembler and the appropriate software can make any consumer good. Japan?
Oil becomes practically worthless. OPEC?
Diamond is synthesized by the ton per minute for building material and gold can be mined cheaply from the sea. South Africa?
Illegal contraband can be made in the home from the same machine providing lunch and a cappuccino. Black market economy.

The world's legal systems and the law enforcement agencies?